Insights into Structure-Activity Relationships of Somatostatin Analogs Containing Mesitylalanine
نویسندگان
چکیده
منابع مشابه
Insights into structure-activity relationships of somatostatin analogs containing mesitylalanine.
The non-natural amino acid mesitylalanine (2,4,6-trimethyl-L-phenylalanine; Msa) has an electron-richer and a more conformationally restricted side-chain than that of its natural phenylalanine counterpart. Taking these properties into account, we have synthesized ten somatostatin analogs containing Msa residues in different key positions to modify the intrinsic conformational flexibility of the...
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ژورنال
عنوان ژورنال: Molecules
سال: 2013
ISSN: 1420-3049
DOI: 10.3390/molecules181214564